How much weight do people regain after stopping?

The most cited figure is from the STEP-1 extension. Participants who lost about 17 percent of body weight on semaglutide regained roughly 12 percent within a year of switching to placebo, which works out to about two thirds of the loss returning. Tirzepatide trials show a similar pattern, with most regain in the first six months off the medication. The average masks wide variation. Research suggests people who keep weighing regularly, hit a protein target, train a couple of times a week, and sleep well tend to regain less, while those who stop tracking and revert to old eating patterns tend to regain more. The medication did not change the math; it temporarily made it easier. Holding the loss is a different, learnable skill. This is educational, not medical advice.