Are Ozempic and Wegovy side effects different?

Side effects are broadly the same on both because the active ingredient is the same: semaglutide. The most common are gastrointestinal: nausea, vomiting, diarrhea, constipation, abdominal pain, and reflux, usually worst during titration and the first week or two after each dose increase. Less common but more serious effects, including pancreatitis, gallbladder disease, and kidney injury tied to dehydration, are listed identically on both labels, and both carry the boxed warning about thyroid C-cell tumors based on rodent studies. Because Wegovy titrates higher, to 2.4 mg weekly, some users report a slightly more intense profile at the top dose than at Ozempic's 2.0 mg ceiling. Talk to your doctor about side effect management and dose pacing.