Which works better for weight loss, Ozempic or Wegovy?

For pure weight outcomes, Wegovy at its 2.4 mg weekly dose tends to edge out Ozempic at its 2.0 mg maximum, because semaglutide weight loss is dose-dependent in clinical trials. The molecule is the same, so the difference traces to the dose ceiling, not to a different drug. That said, the practical winner is usually the option that is on-label for your situation and covered by your insurance, because off-label Ozempic for weight loss is rarely covered and caps at the lower dose. If you have a BMI that meets Wegovy's criteria, an on-label Wegovy prescription is generally the cleaner path. Talk to your doctor about your indication, BMI, and coverage before deciding.